This webcast will be a comparative analysis of conventional heparin-versus bivalirudin-based systemic anticoagulation in adult and pediatric patients supported on extracorporeal membrane oxygenation (ECMO).

Each year, approximately 790,000 patients in the United States develop acute respiratory failure that requires intubation and mechanical ventilation.

COVID-19 is associated with a high prevalence of coagulopathy and venous thromboembolism.

Clinicians are working to understand and formulate an effective treatment for COVID-19-associated acute respiratory distress syndrome.

In a situation where ventilators are in short supply, multiple patients on a single ventilator could be a strategy of last resort.

Enteral feed intolerance occurs frequently during enteral nutrition delivery in the critically ill and is associated with lower enteral nutrition delivery and worse clinical outcomes.

Two previously published trials (ARDS et Curarisation Systematique and Reevaluation of Systemic Early Neuromuscular Blockade) presented equivocal evidence on the effect of neuromuscular blocking agent infusions in patients with acute respiratory distress syndrome.

Rapid delivery of antibiotics is a cornerstone of sepsis therapy, although time targets for specific components of antibiotic delivery are unknown.

Five new recommendations to reduce waste and enhance value in the practice of critical care address invasive devices, proactive liberation from mechanical ventilation, antibiotic stewardship, early mobilization, and providing goal-concordant care.

Sudden cardiac arrest remains a leading cause of premature death worldwide.

Alternative strategies are needed to combat and prevent antibiotic-resistant bacterial infections. Host Ashish K. Khanna, MD, FCCP, FCCM, talks with David R. Cameron, PhD, about the potential for bacteriophage prophylaxis in the context of experimental ventilator-associated pneumonia due to methicillin-resistant Staphylococcus aureus in rats.

Discovery, the Critical Care Research Network's Viral Infection and Respiratory Illness Universal Study creates a real-time COVID-19 registry of current ICU and hospital care patterns.

Explore the need for randomized COVID-19 clinical trials and the difficulties and potential consequences of misinformation with host Ashish K. Khanna, MD, FCCP, FCCM, and Nicholas E. Ingraham, MD.

Review neurologic manifestations of COVID-19 and other severe respiratory viral contagions with host Ludwig H. Lin, MD, and author Christopher P.

Explore the Surviving Sepsis Campaign Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19)

Kyle B. Enfield, MD, and Craig M. Lilly, MD, discuss the newly released guidance for vaping-associated respiratory distress syndrome, published in Critical Care Explorations.

Margaret M. Parker, MD, MCCM, and Jerry J. Zimmerman, MD, PhD, FCCM talk about the trajectory of long-term mortality and significant health-related quality of life disability among children encountering septic shock.

Margaret M. Parker, MD, MCCM, and Mitchell M. Levy, MD, MCCM discuss the Hour-1 Bundle, the controversies of the Surviving Sepsis Campaign, and the future of sepsis.

Kyle B. Enfield, MD, and Marin H. Kollef, MD, discuss the findings and design of the cluster randomized crossover trial on early palliative care consultation in the medical intensive care unit (ICU) published in the December 2019 issue of Critical Care Medicine.

Kyle B. Enfield, MD, and Kimberley J. Haines, PhD, BHSc, discuss implementing post-ICU clinics and peer support groups following critical illness to help reduce the burden of post-intensive care syndrome.

Ranjit Deshpande, MD, and Ruth M. Kleinpell, PhD, RN, ACNP, FCCM, discuss the results of the Choosing Wisely national survey from the Critical Care Societies Collaborative

Ludwig H. Lin, MD, and Ashish K. Khanna, MD, FCCP, FCCM, discuss top-rated abstract, Derivation and Validation of a Novel Opioid-Induced Respiratory Depression Risk Prediction Tool

Ranjit Deshpande, MD, and Simon W. Lam, PharmD, MS, BCPS, BCCCP, FCCM, discuss procalcitonin guidance during different phases of antibiotics management in patients admitted to intensive care units.

Ludwig H. Lin, MD, and Philipp Schuetz, MD, discuss procalcitonin and how it impacts treatment of sepsis.

Kyle B. Enfield, MD, speaks with John W. Devlin, PharmD, FCCM, about the article: Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU

Todd Fraser, MD, speaks with John D. Santamaria, MBBS, MD, FRACP, FCICM, FCCP, about the article: Increasing the Number of Medical Emergency Calls Does Not Improve Hospital Mortality

Todd Fraser, MD, speaks with Rinaldo Bellomo, MD, MBBS, FRACP, FCICM, FAAHMS, about the article Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II

Ranjit Deshpande, MD, speaks with Matthew M. Churpek, MD, MPH, PhD, about the article, Predictors of In-Hospital Mortality After Rapid Response Team Calls in a 274 Hospital Nationwide Sample, published in the July 2018 issue of Critical Care Medicine.

Margaret Parker, MD, MCCM, speaks with Joseph A. Carcillo, MD, about the article, American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock, published in the June 2017 issue of Critical Care Medicine.

Dr. Fraser, MD, speaks with Jean Baptiste Lascarrou, MD, about the article, Antibiotic Therapy in Comatose Mechanically Ventilated Patients Following Aspiration: Differentiating Pneumonia from Pneumonitis, published in Critical Care Medicine.

Ludwig Lin, MD, speaks with Palash Kar, MBBS, about the article, Liberal Glycemic Control in Critically Ill Patients With Type 2 Diabetes: An Exploratory Study, published in Critical Care Medicine.

Ludwig Lin, MD, speaks with Daniel E. Leisman, BS, about the article, Patterns and Outcomes Associated With Timeliness of Initial Crystalloid Resuscitation in a Prospective Sepsis and Septic Shock Cohort, published in Critical Care Medicine.

Margaret Parker, MD, MCCM, speaks with Jeffrey D. Edwards, MD, MA, MAS, about the article, Repeated Critical Illness and Unplanned Readmissions Within 1 Year to PICUs, published in the August 2017 issue of Critical Care Medicine.

Ranjit Deshpande, MD, speaks with James A. Russell, MD, about the article, The Septic Shock 3.0 Definition and Trials: A Vasopressin and Septic Shock Trial Experience, published in the June 2017 issue of Critical Care Medicine.

Kyle Enfield, MD, speaks with Travis J. Moss, MD, MSc, and J. Randall Moorman, MD, about the article, New-Onset Atrial Fibrillation in the Critically Ill, published in the May 2017 issue of Critical Care Medicine.

Margaret Parker, MD, MCCM, speaks with Chani Traube, MD, about the article, Delirium in Critically Ill Children: An International Point Prevalence Study, published in the April 2017 issue of Critical Care Medicine.

Todd Fraser, MD, speaks with Christopher W. Seymour, MD, MSc, about the article, Delays From First Medical Contact to Antibiotic Administration for Sepsis, published in Critical Care Medicine.

Stressful decision making often falls to family members because most patients in the ICU are too ill to participate in decisions. Ranjit Deshpande, MD, speaks with Judy E. Davidson, DNP, RN, FAAN, FCCM, and J. Randall Curtis MD, MPH, about the Guidelines for Family-Centered Care in the Neonatal, Pediatric, and Adult ICU.

Dr. Todd Fraser, MD, speaks with Michael J. Murray, MD, PhD, FCCM, FCCP, about the article, Clinical Practice Guidelines for Sustained Neuromuscular Blockade in the Adult Critically Ill Patient, published in Critical Care Medicine.

Ludwig Lin, MD, speaks with Mitchell M. Levy, MD, MCCM, about the release of the Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016, presented at the 46th Critical Care Congress in Honolulu, Hawaii.

Margaret Parker, MD, MCCM, speaks with David B. Kantor, MD, PhD, about the article, Ultrasound Guidance and Other Determinants of Successful Peripheral Artery Catheterization in Critically Ill Children, published in the December 2016 issue of Pediatric Critical Care Medicine.

Todd Fraser, MD, speaks with Arjen Slooter, MD, PhD, about the article, Long-Term Mental Health Problems After Delirium in the ICU, published in Critical Care Medicine.

Ludwig Lin, MD, speaks with Sachin Yende, MD, MS, about his article, "Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials," published in Critical Care Medicine.

Margaret Parker, MD, MCCM, speaks with Christine Gall, DrPH, about the article, "Pediatric Triage in a Severe Pandemic: Maximizing Survival by Establishing Triage Thresholds," published in the September 2016 issue of Critical Care Medicine.

Todd Fraser, MD, speaks with Joseph L. Nates, MD, MBA, FCCM, about the article, "Intensive Care Unit Admission, Discharge, and Triage Guidelines: A Framework to Enhance Clinical Operations, Development of Institutional Policies, and Further Research," published in Critical Care Medicine.

Todd Fraser, MD, speaks with Alexander B. Levitov, MD, FCCM, FCCP, RDCS. Dr. Levitov is a professor in the division of Pulmonary and Critical Care Medicine and Director of the Ultrasound Training Program at Eastern Virginia Medical School in Norfolk, Virginia.

Margaret Parker, MD, MCCM, speaks with Marin H. Kollef, MD, about the article, Impact of Sepsis Classification and Multidrug-Resistance Status on Outcome Among Patients Treated With Appropriate Therapy, published in Critical Care Medicine.

Michael S. Weinstein, MD, FACS, FCCM, speaks with Zachariah Thomas, PharmD, about the article, A Multicenter Evaluation of Prolonged Empiric Antibiotic Therapy in Adult ICUs in the United States, published in Critical Care Medicine.

Todd Fraser, MD, speaks with Nick Daneman, MD, about the article, Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients, published in Critical Care Medicine.

Todd Fraser, MD, speaks with Derek Wheeler, MD. Dr. Wheeler works as an Intensive Care Specialist at the Cincinnati Children's Hospital Medical Center.

Michael S. Weinstein, MD, FACS, FCCM, speaks with Giovanni Landoni, MD. Dr. Landoni works as an Associate Professor in the Department of Anesthesia and Intensive Care at IRCCS San Raffaele Scientific Institute in Milan, Italy.

Michael S. Weinstein, MD, FACS, FCCM, speaks with Stephen M. Pastores, MD, FCCM. Dr. Pastores serves as Program Director of Critical Care Medicine in the Department of Anesthesiology and Critical Care Medicine at Memorial Sloan-Kettering Cancer Center.

Ludwig Lin, MD, speaks with Michael Blaivas, MD, FACEP, FAIUM. Dr. Blaivas serves as a Professor of Medicine at the University of South Carolina School of Medicine.

Michael S. Weinstein, MD, FACS, FCCM, speaks with C. Terri Hough, MD, MSc. Dr. Hough works as an Associate Professor of Medicine in the Division of Pulmonary and Critical Care Medicine at the University of Washington School of Medicine.

Michael S. Weinstein, MD, FACS, FCCM, speaks with Sean Bagshaw, MD, MSc

Michael S. Weinstein, MD, FACS, FCCM, speaks with Marc G. Jeschke, MD, PhD

Todd Fraser, MD, speaks with Peter Lee, MD, MHS

Ludwig Lin, MD, speaks with Ann M. Parker, MD

Michael S. Weinstein, MD, FACS, FCCM, speaks with Gerard J. Fulda, MD

Michael S. Weinstein, MD, FACS, FCCM, speaks with Daren K. Heyland, MD, FRCPC

Michael S. Weinstein, MD, FACS, FCCM, speaks with C. David Mazer, MD, FRCPC, and Gerard F. Curley, MB, MSc, PhD, FCARCSI

Michael S. Weinstein, MD, FACS, FCCM, speaks with Janice L. Zimmerman, MD, and Courtenay R. Bruce, JD, MA

Michael Weinstein, MD, FACS, speaks with Todd W. Rice, MD, MsC.

Ludwig Lin, MD, speaks with Lars O. Hoiseth, MD.

Todd Fraser, MD, speaks with Kay Choong See, MRCP.

Margaret Parker, MD, MCCM, speaks with Nicole O'Brien, MD

Michael Weinstein, MD, FACS, FCCP, speaks with Jared Chiarchiaro, MD

Margaret Parker, MD, MCCM, speaks with Azra Bihorac, MD, MS, and Charles E. Hobson, MD, MHA

Ludwig Lin, MD, speaks with Jean-Louis Vincent, MD, PhD, FCCM

Todd Fraser, MD, speaks with David Grimaldi, MD, PhD

Ludwig Lin, MD, speaks with Colin R. Cooke, MD.

Michael Weinstein, MD, FACS, FCCP, speaks with the Society of Critical Care Medicine 2015 President, Craig M. Coopersmith, MD, FCCM.

Ludwig H. Lin, MD, speaks with Dorrie K. Fontaine, PhD, RN, FAAN, Dean and Professor at the University of Virginia School of Nursing.

Michael Weinstein, MD, FACS, FCCP, speaks with Ira Cheifetz, MD, FCCM

Todd Fraser, MD, speaks with Allan Garland, MD

Michael Weinstein, MD, FACS, FCCP, speaks with Heidi J. Engel, PT, DPT of UCSF Medical Center.

Michael Weinstein, MD, FACS, FCCP, speaks with Brian Gehlbach, MD, Associate Professor in the Division of Pulmonary, Critical Care, and Occupational Medicine at the University of Iowa Hospitals and Clinics.

Michael Weinstein, MD, FACS, FCCP, speaks with Adam Sapirstein, MD, Associate Professor in the Department of Anesthesia and Critical Care Medicine at the Johns Hopkins School of Medicine.

Michael Weinstein, MD, FACS, FCCP, speaks with Adam Sapirstein, MD, Associate Professor in the Department of Anesthesia and Critical Care Medicine at the Johns Hopkins School of Medicine.

Michael Weinstein, MD, FACS, FCCP, speaks with Jessica Spence, BMR(OT), BSc(Med) MD, a PGY3 Resident at McMaster University.

Michael Weinstein, MD, FACS, FCCP, speaks with Hayley Beth Gershengorn, MD, lead author on an article published in the August Critical Care Medicine.

Michael Weinstein, MD, FACS, FCCP, speaks with Judith Nelson, MD, JD, lead author on an article published in the October Critical Care Medicine.

Michael Weinstein, MD, FACS, FCCP, speaks with David John Murphy, MD, PhD, lead author on an article published in the October Critical Care Medicine.

Michael Weinstein, MD, FACS, FCCP, speaks with Jonathan Elmer, MD, lead author on an article published in the August Critical Care Medicine.

Jeffrey Guy, MD, MSc, MMHC, speaks with Omar Badawi, PharmD, MPH, to discuss his article published in the December Critical Care Medicine.

Michael Weinstein, MD, FACS, FCCP, speaks with J. Randall Curtis, MD, MPH.

Michael Weinstein, MD, FACS, FCCP, speaks with Saqib A. Chaudhry, MD, lead author on an article published in the June Critical Care Medicine.

Michael Weinstein, MD, FACS, FCCP, speaks with David F. Gaieski, MD.

Jeffrey Guy, MD, MSc, MMHC, speaks with David R. Janz, MD, lead author on an article published in the December issue of Critical Care Medicine.

Society of Critical Care Medicine president Carol L. Thompson, PhD, CCRN, ACNP, FCCM, discusses her professional background as a nurse.

Jeffrey Guy, MD, MSc, MMHC, speaks with Juliana Barr, MD, FCCM. The guidelines provide a roadmap for developing integrated, evidence-based, and patient-centered protocols for preventing and treating pain, agitation and delirium.

Michael Weinstein, MD, FACS, FCCP, speaks with Michael Klompas, MD, MPH

Michael Weinstein, MD, FACS, FCCP, speaks with Jill A. Marsteller, PhD, MPP, lead author on an article published in the November Critical Care Medicine

Jeffrey Guy, MD, MSc, MMHC, speaks with Judith Jacobi, PharmD, FCCM, lead author on the new glycemic control guidelines

Michael Weinstein, MD, FACS, FCCP, speaks with Amay Parikh, MD, MBA, MS, lead author on an article published in the October Critical Care Medicine